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PresentationEach syringe of GASTROGARD, containing 6.16 g of oral paste, delivers omeprazole 2.279 g (37% w/w paste). Also contains yellow iron oxide (E172).UsesFor treatment and prevention of gastric ulcers in horses, including foals from 4 weeks oldDosage and administrationGASTROGARD is effective in horses of various breeds and under different management conditions, foals as young as four weeks of age and weighing over 70 kg, and breeding stallions. For oral administration.Treatment of gastric ulcers: one administration per day during 28 consecutive days at the dose rate of 4 mg omeprazole per kg body weight followed immediately by a dosage regimen of one administration per day during 28 consecutive days at the dose rate of 1 mg omeprazole per kg body weight, to reduce the recurrence of gastric ulcers during treatment.Should recurrence occur (confirmed by gastroscopy), re-treatment at a dose rate of 4 mg omeprazole per kg body weight is recommended.Prevention of gastric ulcers: one administration per day at the dose rate of 1mg omeprazole per kg body weight.To deliver GASTROGARD at the treatment dose of 4 mg omeprazole/kg, set the syringe plunger to the appropriate dose division for the horse’s weight. Each full dose division on the syringe plunger delivers sufficient omeprazole to treat 100 kg bodyweight. The contents of one syringe will treat a 575 kg horse at the rate of 4 mg omeprazole per kg body weight.To deliver GASTROGARD at the dose of 1 mg omeprazole/kg, set the syringe plunger to the dose division equivalent to one quarter of the horse's body weight. At this dose, each full division on the syringe plunger will deliver sufficient omeprazole to treat 400 kg body weight. For example, to treat a horse weighing 400kg set the plunger to 100kg.Replace cap after use.Contra-indications, warnings, etcFor animal treatment only.Not recommended for animals under 4 weeks old or weighing less than 70 kg bodyweight.Pregnancy and lactation: Laboratory studies in rats and rabbits have not produced any evidence of a teratogenic effect. In the absence of data during pregnancy and lactation, the use of GASTROGARD in pregnant and lactating mares is not recommended.Interactions: Omeprazole may delay the elimination of warfarin. No other interaction with medicines routinely used in the treatment of horses is expected, although interaction with drugs metabolised by liver enzymes cannot be excluded.Overdose: No undesirable effects related to treatment were observed following daily use for 91 days at omeprazole dosages up to 20 mg/kg in adult horses and in foals older than 2 months. No undesirable effects (including on the semen quality or reproductive behaviour) related to treatment were observed following daily use for 71 days at an omeprazole dosage of 12 mg/kg in breeding stallions. No undesirable effects related to treatment were observed following daily use for 21